Below is a list of runners who have reached 100 marathons in 2006 along with the event and date this milestone was reached.
| Ian Brisland | 26-Nov-06 | Benidorm |
| Brian Smith | 30-Oct-06 | Dublin |
| Pam Storey | 30-Oct-06 | Dublin |
| Colin Cookson | 29-Oct-06 | Snowdonia |
| Linda Major | 08-Oct-06 | Munich |
| Dave King | 23-Jul-06 | Fairlands Valley Challenge |
| Paul Allsop | 14-May-06 | Halstead |
| Osy Waye | 08-Apr-06 | North Pole |