Below is a list of runners who have reached 100 marathons in 2010 along with the event and date this milestone was reached.
| Bob Parmenter | 10-Oct-10 | Leicester Marathon |
| Adam Holland | 10-Oct-10 | Eden Project Marathon |
| Hillary Carter | 19-Sep-10 | Farnham Pilgrims Marathon |
| David Lewis | 19-Sep-10 | Green Chain marathon |
| David Bayley | 12-Sep-10 | Robin Hood Marathon |
| Les Pullen | 05-Sep-10 | Kent Coastal Marathon |
| Patsy Baker | 27-Jun-10 | North Devon Marathon |
| Peter Amos | 18-Jun-10 | Night of Flanders Marathon |
| Michael Haydon | 07-Jun-10 | Cork Marathon |
| Phillip Howells | 30-May-10 | Comrades Marathon |
| Irene Wilson | 23-May-10 | Edinburgh Marathon |
| Tonia Cook | 08-May-10 | Orpington Marafun |
| Tom Wilkie | 18-Apr-10 | Brighton Marathon |
| Anna Finn | 03-Apr-10 | Compton 40 miles |
| Lisa Barry | 21-Mar-10 | Cotswold Marathon |
| John McCullie | 07-Mar-10 | Barcelona Marathon |
| Steve Cooney | 03-Jan-10 | AGM Handicap Marathon |
| David Thompson | 03-Jan-10 | AGM Handicap Marathon |
| Allan Rumbles | 01-Jan-10 | Neujahrs Marathon (Zurich) |